
The Keystone State Ride (KSR) organization supports our riders as they cycle from Pittsburgh to Philadelphia in September (or Pittsburgh to Washington DC). In our first two years we have raised over $80K for cancer research. This critical funding supports cancer research at Penn Medicine’s Abramson Cancer Center (ACC), and hopes to achieve major breakthroughs in cancer therapeutics and care that will ultimately benefit cancer patients globally. The KSR is a 501(c)(3) nonprofit organization (EIN 33-2398245) and all donations are 100% tax deductible. The KSR strives to build community among its participants, encourage diversity, and maintain an environment free from discrimination where participants treat each other with respect, dignity, and courtesy.
"Dealing with cancer is like cycling up a steep hill. You just have to put it in a low gear and keep moving forward" - Dave Wellborn, five time cancer survivor.

The KSR will be held every September. Registration includes transportation to Pittsburgh, hotels, luggage transfers, and van support. Meals are expected to be paid for by the rider, although some breakfasts will be provided by the hotel.
The KSR culminates with the Breakthrough Bike Challenge Ride at the Daniel Boone Homestead where we celebrate the success of both fundraisers for cancer research.
Refer to the "Ride Description" below for daily mileage, elevation details, and rest stops. Select this link to see the route: Ride with GPS Routes

Pittsburgh to Philly PA OR Pittsburgh to Hancock MD
New in 2026: Great Allegheny Passage (GAP). 3-4 Days
Registration Link: KSR BikeReg
Pittsburgh to Philly PA OR Pittsburgh to Hancock MD
Daniel Boone Homestead, Reading PA
Link to: Breakthrough Challenge
Daniel Boone Homestead, Reading PA
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